Illuminator, a desktop program for mutation detection using short-read clonal sequencing
نویسندگان
چکیده
منابع مشابه
Haplotype-based variant detection from short-read sequencing
The direct detection of haplotypes from short-read DNA sequencing data requires changes to existing small-variant detection methods. Here, we develop a Bayesian statistical framework which is capable of modeling multiallelic loci in sets of individuals with non-uniform copy number. We then describe our implementation of this framework in a haplotype-based variant detector, FreeBayes. 1 Motivati...
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ژورنال
عنوان ژورنال: Genomics
سال: 2011
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2011.05.004